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IL1RAP – Interleukin-1 Receptor Accessory Protein - IPOhub
Species Mouse Transcripts. 4 RefSeqs (NM) Transcript Type Coding Product Type Silencer® Select Availability. Made to Order. Catalog # 4390771 21 Feb 2019 A possible involvement of the gene IL1RAP (interleukin-1 receptor-associated protein) in the pathogenesis of Alzheimer's disease (AD) has We need your help in understanding the impact of Ensembl in your research. Please take the EMBL-EBI impact survey that includes Ensembl (15 min). Full gene name according to HGNC.
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cell lines with IL1RAP gene mutations from the CCLE Cell Line Gene Mutation Profiles dataset. CHEA Transcription Factor Binding Site Profiles transcription factor binding site profiles with transcription factor binding evidence at the promoter of IL1RAP gene from the CHEA Transcription Factor Binding Site Profiles dataset. Since IL1RAP is a critical subunit of the functional interleukin-1 receptor (IL-1R), we investigated the effect of these variants on IL-1R subunit function. When stimulated with IL-1β, peripheral blood mononuclear cells from the siblings with SSNS produced markedly lower levels of cytokines compared with cells from healthy family members. IL1RAP; interleukin 1 receptor accessory protein: 4615 : Controlling gene expression in response to stress.
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Order GeneTex's IL1RAP peptide directly at Bio-Connect. Catalog number: GTX26105. Packing: 50 ug.
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IL1RAP (Interleukin 1 Receptor Accessory Protein) is a Protein Coding gene. Diseases associated with IL1RAP include Marginal Corneal Ulcer and Indolent Plasma Cell Myeloma. Among its related pathways are Bacterial infections in CF airways and MAPK signaling pathway. IL1RAP interleukin 1 receptor accessory protein [ (human)] Associations of IL1RAP and IL1RL1 gene polymorphisms with obesity and inflammation mediators.
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Ahmad IL1RAP is required in order to activate IL-1 receptor signaling16 (Reporter gene assay). Antigen: IL1RAP (interleukin 1 receptor accessory protein) Clonality: polyclonal. Clone: Conjugation: unconjugated. Epitope: Host: Rabbit Isotype: none NPR1.
Since IL1RAP is a critical subunit of the functional interleukin-1 receptor (IL-1R), we investigated the effect of these variants on IL-1R subunit function. When stimulated with IL-1β, peripheral blood mononuclear cells from the siblings with SSNS produced markedly lower levels of cytokines compared with cells from healthy family members. IL1RAP; interleukin 1 receptor accessory protein: 4615 : Controlling gene expression in response to stress. Journal: Nat Rev Genet 12:833-45 (2011) DOI:
IL1RAP gene expression in Bgee.
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Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits.